Nezelot syndrome and the diseases easily confused?

Should be differentiated from immune deficiency diseases.

Nezelot syndrome, which checks should be done?

Shows significantly reduced lymphocytes, serum IgG, IgA, IgM volume can be normal, but individual components can increase or decrease, and the antibody formation was defective. A variety of antigen delayed hypersensitivity skin test does not react. Phytohemagglutinin, allogeneic cell antigen Deng Jun difficult to bring in patients with lymphocyte transformation. Lymph node biopsy in thymus-dependent area, see the lack of lymphoid tissue, bone marrow plasma cells can be seen.


Chest X-ray can show the thymus smaller or can not see.

Nezelof syndrome:What are the performance and how to diagnose?

When infants and young children from recurring infectious diseases, such as pneumonia, Candida albicans disease, virus, Pseudomonas aeruginosa, Pneumocystis carinii, non-tuberculous mycobacterial infections. Oral thrush, fever, indigestion, etc. can cause children are stunted, and may have tonsil dysplasia, no symptoms of thyroid abnormalities.



According to history, clinical manifestations, laboratory tests, chest X-ray examination. Can be diagnosed.

Nezelof syndrome is caused by what the?

(A) causes of morbidity This syndrome is autosomal recessive primary immunodeficiency disease. (B) the pathogenesis of Pathological manifestations of hypoplasia in the thymus, lymph nodes and spleen dependence of the lack of lymphoid tissue area.